Endocrine Abstracts

Introduction: Previous clinical studies on effect of statins treatment on testosterone levels have produced mixed results. The aim of the present study is to evaluate the association between statin therapy and hormonal parameters in a large series of subjects seeking medical care at our Unit for ED.Methods: A consecutive series of 3484 (mean age 51.6±13.1 years) patients with ED was studied.Several hormonal and biochemical par...

Introduction: Although it is well established that all the aspects of male reproduction are hormonally regulated, the endocrine control of the ejaculatory reflex is still not completely clarified. Sex steroids, thyroid and pituitary hormones (oxytocin and prolactin) have been proposed to control the ejaculatory process at various levels, however, only a few reports are currently available. The aim of the present study is to evaluate the contribution of testosterone, TSH and pr...

Introduction: Although testosterone has been suggested to play a protective role against the development of atherosclerosis, studies demonstrating an association between low testosterone, and incident major adverse cardiovascular events (MACE) are scanty in the general population and absent in subjects with erectile dysfunction (ED). The aim of this study is to investigate whether low testosterone in subjects with ED predict incident fatal or non fatal MACE.<p class="abste...

Introduction: No study has ever assessed the possible association of penile blood flow (PBF) and the relational component of sexual function with incident major cardiovascular events (MACE). The aim of this study is to investigate whether severity of erectile dysfunction (ED), PBF and other factors related to a couple’s relationship predict incident (MACE).Methods: A subset of 1687 patients was longitudinal studied. Different clinical, biochemical a...

Introduction: Concern about a testosterone-induced PSA increase is often perceived as one of the main limitations in treating hypogonadism even when it is symptomatic, such as in subjects with sexual dysfunction (SD). The aim of the present study is to evaluate the relationship between testosterone (T) and PSA levels in subjects with SD.Methods: We retrospectively evaluated the relationship between T and PSA in 2291 subjects seeking medical care at our O...